• Abdominal symptoms in general practice: Frequency, cancer suspicions raised, and actions taken by GPs in six European countries. Cohort study with prospective registration of cancer 

      Holtedahl, Knut A.; Borgquist, Lars; Donker, Gé A.; Buntinx, Frank; Weller, David; Braaten, Tonje; Hjertholm, Peter; Månsson, Jörgen; Strandberg, Eva Lena; Campbell, Christine; Ellegaard, Lisbeth; Parajuli, Ranjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06)
      Background<br> Abdominal symptoms are diagnostically challenging to general practitioners (GPs): although common, they may indicate cancer. In a prospective cohort of patients, we examined abdominal symptom frequency, initial diagnostic suspicion, and actions of GPs in response to abdominal symptoms.<p> Methods<br> Over a 10-day period, 493 GPs in Norway, Denmark, Sweden, Belgium, the Netherlands, ...
    • The Association between Lifetime Smoking Exposure and Breast Cancer Mortality – Results from a Norwegian Cohort 

      Bjerkaas, Eivind; Gram, Inger Torhild; Parajuli, Ranjan; Weiderpass, Elisabete; Mascarinec, G; Engeland, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      Several recent cohort studies have found an association between smoking and breast cancer, but the association between lifetime smoking exposure and breast cancer mortality is less well described. We examined whether smoking before breast cancer diagnosis is a predictor of breast cancer mortality in a large cohort with more than 4.1 million years of follow-up, with a special focus on women who ...
    • Cigarette smoking and colorectal cancer mortality among 602,242 Norwegian males and females 

      Parajuli, Ranjan; Bjerkaas, Eivind; Tverdal, Aage; Le Marchand, Loïc; Weiderpass, Elisabete; Gram, Inger Torhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      Background: Colorectal cancer (CRC) is one of the main cancer types, with high incidence and mortality in Norway. We examined the association between different measures of smoking exposure and CRC mortality overall and by subsite in a large Norwegian cohort. Methods: We followed 602,242 participants from four Norwegian health surveys, aged 19–67 years at enrollment between 1972 and 2003 by linkage ...
    • Smoking and incidence and mortality of colorectal cancer 

      Parajuli, Ranjan (Doctoral thesis; Doktorgradsavhandling, 2014-06-05)
      Smoking is one of the most important causes of cancer and premature death worldwide. Two different reports, the most recent monograph published by International Agency for Research on Cancer (IARC) in 2012 and the Unites States Surgeon General’s report of 2014, concluded that smoking is risk factor for both colon and rectal cancer. In addition to being one of the most common cancers in Norway, ...
    • Smoking duration before first childbirth: an emerging risk factor for breast cancer? Results from 302,865 Norwegian women 

      Bjerkaas, Eivind; Parajuli, Ranjan; Weiderpass, Elisabete; Engeland, Anders; Gertraud, Maskarinec; Selmer, Randi; Gram, Inger Torhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Purpose: Recently, The International Agency for Research on Cancer classified cigarette smoking as possibly carcinogenic to the human breast. Since some new cohort studies have suggested that this risk is confined to women who started to smoke before first childbirth, we wanted to examine the association between smoking and breast cancer, with a focus on time of smoking initiation in relation to the ...
    • Smoking increases rectal cancer risk to the same extent in women as in men: results from a Norwegian cohort study 

      Parajuli, Ranjan; Bjerkaas, Eivind; Aage, Tverdal; Le Marchand, Loïc; Weiderpass, Elisabete; Gram, Inger Torhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-05-06)
      Background: Smoking has recently been established as a risk factor for rectal cancer. We examined whether the smoking-related increase in rectal cancer differed by gender. Methods: We followed 602,242 participants (49% men), aged 19 to 67 years at enrollment from four Norwegian health surveys carried out between 1972 and 2003, by linkage to Norwegian national registries through December 2007. ...
    • Social inequalities and smoking-associated breast cancer - Results from a prospective cohort study 

      Bjerkaas, Eivind; Parajuli, Ranjan; Engeland, Anders; Maskarinec, Gertraud; Weiderpass, Elisabete; Gram, Inger Torhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01-22)
      Objective. The association between smoking and breast cancer has been found in most recent, large cohort studies. We wanted to investigate how smoking-associated breast cancer varies by level of education, a wellestablished measure of socioeconomic status. <p>Methods. We included 302,865 women with 7490 breast cancer cases. Participants were assigned to low, moderate or high level of education ...
    • Symptoms and signs of colorectal cancer, with differences between proximal and distal colon cancer: a prospective cohort study of diagnostic accuracy in primary care 

      Holtedahl, Knut; Borgquist, Lars; Donker, Gé A.; Buntinx, Frank; Weller, David; Campbell, Christine; Månsson, Jörgen; Hammersley, Victoria; Braaten, Tonje; Parajuli, Ranjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-08)
      <i>Background</i> - In an abdominal symptom study in primary care in six European countries, 511 cases of cancer were recorded prospectively among 61,802 patients 16 years and older in Norway, Denmark, Sweden, Netherlands, Belgium and Scotland. Colorectal cancer is one of the main types of cancer associated with abdominal symptoms; hence, an in-depth subgroup analysis of the 94 colorectal cancers ...
    • Symptoms and signs of urogenital cancer in primary care 

      Holtedahl, Knut Arne; Borgquist, Lars; Donker, Gé A.; Buntinx, Frank; Weller, David; Campbell, Christine; Månsson, Jörgen; Hammersley, Victoria; Braaten, Tonje Bjørndal; Parajuli, Ranjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-26)
      Background - Urogenital cancers are common, accounting for approximately 20% of cancer incidence globally. Cancers belonging to the same organ system often present with similar symptoms, making initial management challenging. In this study, 511 cases of cancer were recorded after the date of consultation among 61,802 randomly selected patients presenting in primary care in six European countries: a ...
    • A Systematic Review of the Prevalence of Gestational Diabetes in Norway 

      Behboudi-Gandevani, Samira; Parajuli, Ranjan; Vaismoradi, Mojtaba (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-03)
      Gestational diabetes mellitus (GDM) is a major public health problem and a threat to maternal and child health. There is a lack of integrated and systematically synthesized knowledge about the prevalence GDM in Norway. Therefore, this systemic review aimed to present the best available peer-reviewed published evidence from the past 20 years about the prevalence of GDM in Norway. A comprehensive ...